# Association between metabolic syndrome, diabetes mellitus, inflammation and cognitive dysfunctions in schizophrenia: a cross-sectional analysis

**URL:** <https://schizophreniasupport.discourse.group/t/association-between-metabolic-syndrome-diabetes-mellitus-inflammation-and-cognitive-dysfunctions-in-schizophrenia-a-cross-sectional-analysis/477>\
**Category:** News on schizophrenia and mental health matters\
**Created:** [December 17, 2025, 4:01pm UTC](https://schizophreniasupport.discourse.group/t/association-between-metabolic-syndrome-diabetes-mellitus-inflammation-and-cognitive-dysfunctions-in-schizophrenia-a-cross-sectional-analysis/477 "2025-12-17T16:01:20Z")\
**Posts on this page:** 2\
**Page:** 1

<div class="post-metadata">

**Author:** ![everhopeful](https://yyz2.discourse-cdn.com/flex012/user_avatar/schizophreniasupport.discourse.group/everhopeful/32/605_2.png) [@everhopeful](https://schizophreniasupport.discourse.group/u/everhopeful)\
**Post date:** [December 17, 2025, 4:01pm UTC](https://schizophreniasupport.discourse.group/t/association-between-metabolic-syndrome-diabetes-mellitus-inflammation-and-cognitive-dysfunctions-in-schizophrenia-a-cross-sectional-analysis/477/1 "2025-12-17T16:01:20Z")

</div>

> **[Association between metabolic syndrome, diabetes mellitus, inflammation and...](https://pubmed.ncbi.nlm.nih.gov/41402355/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1Jks6COFDAP1wm2oOTJE-A4QQ8EnzOQLuh2br9UD5wIdenCA00&fc=20240119115713&ff=20251217105844&v=2.18.0.post22%2B67771e2)**
>
> Metabolic syndrome (MetS) and diabetes mellitus (DM) are frequent in schizophrenia (SCZ) and have been linked to cognitive impairment and low-grade inflammation. In this cross-sectional study of adults with DSM-5 SCZ (N = 218; SCZ = 103, SCZ+MetS =...

> Across the cohort, higher IL-6 and fasting glucose were associated with lower attention and delayed memory. We conclude that DM status and higher IL-6 were most consistently associated with poorer attention and delayed memory in SCZ

---

<div class="post-metadata">

**Author:** ![SzSupportAdmin](https://yyz2.discourse-cdn.com/flex012/user_avatar/schizophreniasupport.discourse.group/szsupportadmin/32/334_2.png) [@SzSupportAdmin](https://schizophreniasupport.discourse.group/u/SzSupportAdmin)\
**Post date:** [December 23, 2025, 10:00am UTC](https://schizophreniasupport.discourse.group/t/association-between-metabolic-syndrome-diabetes-mellitus-inflammation-and-cognitive-dysfunctions-in-schizophrenia-a-cross-sectional-analysis/477/2 "2025-12-23T10:00:17Z")

</div>