# FDA recommends another large trial for new schizophrenia drug **URL:** \ **Category:** News on schizophrenia and mental health matters\ **Created:** [December 23, 2025, 1:11pm UTC](https://schizophreniasupport.discourse.group/t/fda-recommends-another-large-trial-for-new-schizophrenia-drug/753 "2025-12-23T13:11:27Z")\ **Posts on this page:** 3\ **Page:** 1
**Author:** ![everhopeful](https://yyz2.discourse-cdn.com/flex012/user_avatar/schizophreniasupport.discourse.group/everhopeful/32/605_2.png) [@everhopeful](https://schizophreniasupport.discourse.group/u/everhopeful)\ **Post date:** [December 23, 2025, 1:11pm UTC](https://schizophreniasupport.discourse.group/t/fda-recommends-another-large-trial-for-new-schizophrenia-drug/753/1 "2025-12-23T13:11:27Z")
> **[FDA recommends another large trial for new schizophrenia drug](https://www.stocktitan.net/news/RVPH/reviva-announces-regulatory-update-regarding-the-development-of-brey1evipk8z.html)** > > FDA pre-NDA feedback urges a second Phase 3 trial of brilaroxazine in schizophrenia. RECOVER-2 is planned for H1 2026, subject to sufficient financing. > Reviva (NASDAQ: RVPH) announced a regulatory update on Dec 23, 2025 following a pre-NDA meeting with the FDA about brilaroxazine for schizophrenia. The FDA provided written feedback recommending a second Phase 3 trial to generate additional efficacy and safety data prior to an NDA submission. ---
**Author:** ![SzSupportAdmin](https://yyz2.discourse-cdn.com/flex012/user_avatar/schizophreniasupport.discourse.group/szsupportadmin/32/334_2.png) [@SzSupportAdmin](https://schizophreniasupport.discourse.group/u/SzSupportAdmin)\ **Post date:** [December 23, 2025, 1:16pm UTC](https://schizophreniasupport.discourse.group/t/fda-recommends-another-large-trial-for-new-schizophrenia-drug/753/2 "2025-12-23T13:16:45Z")
Im reasonably happy with Abilify maintena(spelling?) right now. It would take proven reductions in negative symptoms probably to get me to switch again. Or some other major benefit. And even then, I would probably wait it out for a couple/few years. I dont like risking unknown long term use side effects on new drugs. ---
**Author:** ![SzSupportAdmin](https://yyz2.discourse-cdn.com/flex012/user_avatar/schizophreniasupport.discourse.group/szsupportadmin/32/334_2.png) [@SzSupportAdmin](https://schizophreniasupport.discourse.group/u/SzSupportAdmin)\ **Post date:** [December 29, 2025, 12:15am UTC](https://schizophreniasupport.discourse.group/t/fda-recommends-another-large-trial-for-new-schizophrenia-drug/753/3 "2025-12-29T00:15:39Z")