# I want to try clozapine **URL:** \ **Category:** Medications\ **Created:** [July 27, 2026, 5:41pm UTC](https://schizophreniasupport.discourse.group/t/i-want-to-try-clozapine/7452 "2026-07-27T17:41:32Z")\ **Posts on this page:** 20\ **Page:** 1
**Author:** ![beans782](https://avatars.discourse-cdn.com/v4/letter/b/f07891/32.png) [@beans782](https://schizophreniasupport.discourse.group/u/beans782)\ **Post date:** [July 27, 2026, 5:41pm UTC](https://schizophreniasupport.discourse.group/t/i-want-to-try-clozapine/7452/1 "2026-07-27T17:41:32Z")
Currently on xeplion and aripiripazole Still hearing things that aren’t there and paranoid thoughts. Could clozapine resolve this? ---
**Author:** ![Milk](https://yyz2.discourse-cdn.com/flex012/user_avatar/schizophreniasupport.discourse.group/milk/32/12267_2.png) [@Milk](https://schizophreniasupport.discourse.group/u/Milk)\ **Post date:** [July 27, 2026, 5:45pm UTC](https://schizophreniasupport.discourse.group/t/i-want-to-try-clozapine/7452/2 "2026-07-27T17:45:02Z")
No,not really .. I’m long time on it,and have voices .. But it’s best med for me,I can sleep and function .. I take 300mgs/day ---
**Author:** ![Corion](https://yyz2.discourse-cdn.com/flex012/user_avatar/schizophreniasupport.discourse.group/corion/32/8884_2.png) [@Corion](https://schizophreniasupport.discourse.group/u/Corion)\ **Post date:** [July 27, 2026, 5:46pm UTC](https://schizophreniasupport.discourse.group/t/i-want-to-try-clozapine/7452/3 "2026-07-27T17:46:50Z")
Clozapine didnt help my voices either still on 150mg a day ---
**Author:** ![beans782](https://avatars.discourse-cdn.com/v4/letter/b/f07891/32.png) [@beans782](https://schizophreniasupport.discourse.group/u/beans782)\ **Post date:** [July 27, 2026, 5:47pm UTC](https://schizophreniasupport.discourse.group/t/i-want-to-try-clozapine/7452/4 "2026-07-27T17:47:08Z")
But does it help more then xeplion? ---
**Author:** ![Milk](https://yyz2.discourse-cdn.com/flex012/user_avatar/schizophreniasupport.discourse.group/milk/32/12267_2.png) [@Milk](https://schizophreniasupport.discourse.group/u/Milk)\ **Post date:** [July 27, 2026, 5:49pm UTC](https://schizophreniasupport.discourse.group/t/i-want-to-try-clozapine/7452/5 "2026-07-27T17:49:27Z")
It’s different,but haven’t tried xeplion,but been on Risperdal Consta for six months .. I think that are different mechanism meds .. ---
**Author:** ![WhiteRaven](https://yyz2.discourse-cdn.com/flex012/user_avatar/schizophreniasupport.discourse.group/whiteraven/32/5401_2.png) [@WhiteRaven](https://schizophreniasupport.discourse.group/u/WhiteRaven)\ **Post date:** [July 27, 2026, 5:50pm UTC](https://schizophreniasupport.discourse.group/t/i-want-to-try-clozapine/7452/6 "2026-07-27T17:50:12Z")
I’m on clozapine…350 mg per day. I still have voices but my psychotic symptoms are very mild. It lets me live independently most of the time. I don’t like the increased appetite, and despite using atropine drops I still drool when I sleep. ---
**Author:** ![Corion](https://yyz2.discourse-cdn.com/flex012/user_avatar/schizophreniasupport.discourse.group/corion/32/8884_2.png) [@Corion](https://schizophreniasupport.discourse.group/u/Corion)\ **Post date:** [July 27, 2026, 5:51pm UTC](https://schizophreniasupport.discourse.group/t/i-want-to-try-clozapine/7452/7 "2026-07-27T17:51:33Z")
Not sure i haven’t tried xeplion ---
**Author:** ![Milk](https://yyz2.discourse-cdn.com/flex012/user_avatar/schizophreniasupport.discourse.group/milk/32/12267_2.png) [@Milk](https://schizophreniasupport.discourse.group/u/Milk)\ **Post date:** [July 27, 2026, 5:58pm UTC](https://schizophreniasupport.discourse.group/t/i-want-to-try-clozapine/7452/8 "2026-07-27T17:58:07Z")
Xeplion is same as Paliperidone (invega) It’s European brand. ---
**Author:** ![Joker](https://yyz2.discourse-cdn.com/flex012/user_avatar/schizophreniasupport.discourse.group/joker/32/13470_2.png) [@Joker](https://schizophreniasupport.discourse.group/u/Joker)\ **Post date:** [July 27, 2026, 6:01pm UTC](https://schizophreniasupport.discourse.group/t/i-want-to-try-clozapine/7452/9 "2026-07-27T18:01:42Z")
I wish I said yes to it a long time ago but I thought I knew better than the doctors Not that starting it was much of a choice in the end 🤷 ---
**Author:** ![Lenny](https://avatars.discourse-cdn.com/v4/letter/l/ba8739/32.png) [@Lenny](https://schizophreniasupport.discourse.group/u/Lenny)\ **Post date:** [July 27, 2026, 6:06pm UTC](https://schizophreniasupport.discourse.group/t/i-want-to-try-clozapine/7452/10 "2026-07-27T18:06:16Z")
I’m not a pdoc, but I think they work better together, I do clozapine and every 3 months I have Paliperidone injections. My veredict? Clozapine is a must to do drug, and one of the most effective for treating sz, my meds were always clozapine with something, so since I start medication I always used clozapine. Voices didn’t go away, but they got quieter and more manageable. ---
**Author:** ![Corion](https://yyz2.discourse-cdn.com/flex012/user_avatar/schizophreniasupport.discourse.group/corion/32/8884_2.png) [@Corion](https://schizophreniasupport.discourse.group/u/Corion)\ **Post date:** [July 27, 2026, 6:12pm UTC](https://schizophreniasupport.discourse.group/t/i-want-to-try-clozapine/7452/11 "2026-07-27T18:12:39Z")
Ah gotcha then I have tried it. I had pretty severe akathesia on it and had to take a lot of cogentin that made me super thirsty ---
**Author:** ![roxanna](https://yyz2.discourse-cdn.com/flex012/user_avatar/schizophreniasupport.discourse.group/roxanna/32/16558_2.png) [@roxanna](https://schizophreniasupport.discourse.group/u/roxanna)\ **Post date:** [July 27, 2026, 8:06pm UTC](https://schizophreniasupport.discourse.group/t/i-want-to-try-clozapine/7452/12 "2026-07-27T20:06:54Z")
Clozapine does not agree with me. Plus the blood tests. No thank you. ---
**Author:** ![Om\_Sadasiva](https://yyz2.discourse-cdn.com/flex012/user_avatar/schizophreniasupport.discourse.group/om_sadasiva/32/179_2.png) [@Om\_Sadasiva](https://schizophreniasupport.discourse.group/u/Om_Sadasiva)\ **Post date:** [July 28, 2026, 11:09am UTC](https://schizophreniasupport.discourse.group/t/i-want-to-try-clozapine/7452/13 "2026-07-28T11:09:30Z")
I’ve been taking clozapine for 7 years. It’s one of the best meds but doesn’t make me totally sane. I still have symptoms ---
**Author:** ![Zoe](https://yyz2.discourse-cdn.com/flex012/user_avatar/schizophreniasupport.discourse.group/zoe/32/7475_2.png) [@Zoe](https://schizophreniasupport.discourse.group/u/Zoe)\ **Post date:** [July 28, 2026, 12:25pm UTC](https://schizophreniasupport.discourse.group/t/i-want-to-try-clozapine/7452/14 "2026-07-28T12:25:33Z")
Clozapine works well for some people; just a heads up that it might knock you out like an hour or so after you take it. This is from anecdotal evidence ---
**Author:** ![see121](https://avatars.discourse-cdn.com/v4/letter/s/7cd45c/32.png) [@see121](https://schizophreniasupport.discourse.group/u/see121)\ **Post date:** [July 28, 2026, 8:13pm UTC](https://schizophreniasupport.discourse.group/t/i-want-to-try-clozapine/7452/15 "2026-07-28T20:13:04Z")
I take it at night. It helps me sleep. ---
**Author:** ![Mr\_Hope](https://yyz2.discourse-cdn.com/flex012/user_avatar/schizophreniasupport.discourse.group/mr_hope/32/7092_2.png) [@Mr\_Hope](https://schizophreniasupport.discourse.group/u/Mr_Hope)\ **Post date:** [July 28, 2026, 10:22pm UTC](https://schizophreniasupport.discourse.group/t/i-want-to-try-clozapine/7452/16 "2026-07-28T22:22:08Z")
Have you already tried zyprexa? It’s considered by many as the second heaviest drug, only next to clozapine. ---
**Author:** ![temperature](https://avatars.discourse-cdn.com/v4/letter/t/ac91a4/32.png) [@temperature](https://schizophreniasupport.discourse.group/u/temperature)\ **Post date:** [August 13, 2026, 6:36am UTC](https://schizophreniasupport.discourse.group/t/i-want-to-try-clozapine/7452/17 "2026-08-13T06:36:07Z")
I’m on generic Zyprexa (olanzapine). I take 22.5mg per day every evening. I know this is a little elevated, but I was on 30mg for over two continuous years. It was my Mother’s advice to reduce the dose with a goal target dosage of 20mg per day. I’m just glad to finally be 100% compliant with treatment, as well as having an open mind. I am on the lowest dose of olanzapine I have been on over the past nine consecutive years. And it’s working out so far, which I am proud of. I remember whenever it was my idea to reduce my medication, I always ended up going off the deep end, metaphorically. So I have learned to trust. ---
**Author:** ![Mr\_Hope](https://yyz2.discourse-cdn.com/flex012/user_avatar/schizophreniasupport.discourse.group/mr_hope/32/7092_2.png) [@Mr\_Hope](https://schizophreniasupport.discourse.group/u/Mr_Hope)\ **Post date:** [August 13, 2026, 9:31am UTC](https://schizophreniasupport.discourse.group/t/i-want-to-try-clozapine/7452/18 "2026-08-13T09:31:00Z")
Welcome to the forum @temperature I guess being compliant is the way to go. Trying to quit meds on my own never went well. Glad you got to a lower dose, you probably feel better. ---
**Author:** ![mouse1977](https://avatars.discourse-cdn.com/v4/letter/m/c77e96/32.png) [@mouse1977](https://schizophreniasupport.discourse.group/u/mouse1977)\ **Post date:** [August 13, 2026, 1:05pm UTC](https://schizophreniasupport.discourse.group/t/i-want-to-try-clozapine/7452/19 "2026-08-13T13:05:17Z")
Personally I wouldn’t because when I tried clozapine I passed out every day until I got used to it. Unfortunately I was sedated against my will. I would pass out every night, was very fat and hungry, had breathing troubles and couldn’t communicate. What a nightmare… ---
**Author:** ![Eternalaether](https://yyz2.discourse-cdn.com/flex012/user_avatar/schizophreniasupport.discourse.group/eternalaether/32/85_2.png) [@Eternalaether](https://schizophreniasupport.discourse.group/u/Eternalaether)\ **Post date:** [August 17, 2026, 2:15pm UTC](https://schizophreniasupport.discourse.group/t/i-want-to-try-clozapine/7452/20 "2026-08-17T14:15:55Z")
Clozapine is an awful drug; check Gemini/ChatGPT for the full side effect profile man. I don’t think any med can get rid of voices tbh. [Next page](https://schizophreniasupport.discourse.group/t/i-want-to-try-clozapine/7452.md?page=2)