I’m in the process of tapering off or lowering Seroquel

So I’m went down from 900 mg of Seroquel a half year ago to 300 mg by now and will be off of it in 3 months time.

I keep my 400 mg Clopixol depot every 3 weeks and two akineton pills.

Around 4 years ago I quit 160 mg Ziprasidone.

Keep in mind that I had 3 antipsychotics at the same time and now am going down to just one by injection.

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Hello @Relaxe ,

I sincerely hope that it’s going ok for you.

I am in some ways in no position at all to offer advice or to lecture, having recently tried to (very, very) slowly reduce my main AP, to devastating effect on my mental health.

But if I have learned anything, it is about how very, very slowly one has to reduce medication.

The most up-to-date advice is to do what’s called ‘hyperbolic tapering’ (feel free to google that one).

What this basically means, is to never reduce the drug by more than 5-10% of the previous months’s dose.

In other words: NOT 5-10% of the STARTING dose, but maximum 5-10% of the PREVIOUS MONTH’s dose.

So the effect is that the reduction is not linear. In other words, if you were so inclined, and drew this on a mathematical graph, it would be a curve, and not a straight line, with a higher drop at the start, and a slower, and slower reduction/drop the lower you go.

So, briefly speaking: I personally wouldn’t reduce by more than 5-10% of the previous month’s dose, and then hold it, and see how you feel.

Also: I have heard that the final 1/3rd and the path to zero is by far the hardest of all. So be prepared for withdrawal symptoms. (Although obviously I hope that this doesn’t happen for you.)

I really hope it goes well for you, but also would add that there’s no shame at all if you get to a certain lower dose, and can’t seem to get any lower.

Good luck!

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Yes you speak the Truth that the 10 % tapering is the only way to go when you are tapering a single antipsychotic. Yes that’s true you are a very intelligent person that you examined the tapering princippels

.

But the Clopixol is my main antipsychotics and that blocks D2 receptors by 80 %.

300 mg Seroquel D2 antagonism 50 %

200 mg 40 %

100 mg 30 %

So Seroquel doesn’t work like an antipsychotic at those doses.

Because my psychosis is treated with Clopixol I think I can move down in Seroquel quicker.

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But I start to questioning my decision cause there are other reason for me taking Seroquel than psychosis.

  1. Controls my mood
  2. Prevents me from feeling drunk when drinking.
  3. Prevents OCD

If I took it for psychosis only I’d stop it but I need it for the other things.

Did your Dr approve going off it? Are you doing this on your own?

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My doctor would gladly approve on that because he doesn’t know me that well.

But when I realize that the meds saves me from getting drunk I think that the best thing I can do is to stay on the 300 mg of Seroquel.

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If you know your Dr would approve, why haven’t you brought it up?

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You really should be making these decisions with a doctor. Messing around with your medications yourself is usually a recipe for disaster. I know. I’ve done it myself.

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Hello,

I 100% agree with what’s been said, and think that any reductions or changes should really be made with a doctor’s help.

Thanks

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What you say is really true.

To prove to myself and the doctor that the option is realistic.

I really think you should do it under a drs care because once you lose insight you won’t realize you need help

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What @Lilyofthevalley said is very, very true! Due to severe depression years ago, I stopped taking every med I was on cold turkey. I was so depressed that I didn’t even notice withdrawal symptoms. Anyhow, I thought I was fine for months. Then, all of a sudden, I was in a psych ward. So there’s a chance you could pull it off for a little while like I did… but I guarantee it isn’t worth it in the end. Please consult with your doctor.

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You know as I said the Clopixol depot injection I have protect me from psychotic thought and not that much the Seroquel but at the same time I’m starting to realize that the 300 mg Seroquel protect me from very seriously alcohol abuse so yes I’ll rapport back to my doctor. I realize now that I should avoid the antipsychiatry forums because I realize that Ive come down to a dose of antipsychotics that protect me and others from my psychosis and I think that it’s unsafe to change meds anymore.

The anti-med people are wack-jobs. These medications are proven to work.

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I agree. I’m the prove because I’ve had Clopixol depot for 29 years and Seroquel for 14 years.

What brought me to the antipsychiatry forum was the fact that the psychiatry had me on tó much and many meds at the same time. But now where I’m on a low dose of two antipsychotics I’m ready to accept my treatment as it is now.

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Do you take the Seroquel in the morning? It makes me loopy.

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Twice a day. 100 mg morning and 200 mg evening

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This is so true. Avoid those dark corners of the net. A lot of those people had one bad experience with psychiatry and they paint it all to be a Luciferian conspiracy.

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