Supplements, weight loss medication, new antipsychotic backed by studies, links of studies provided

Without side effects shown in most studies, please do not stop taking your antipsychotic, studies are all in adjunction with antipsychotic, the supplement below are at dosage or contain elements not commonly found in our diet

For positive symptoms

L theanine 400 mg and below , The effects of L-theanine supplementation on the outcomes of patients with mental disorders: a systematic review - PMC

For negative symptom

Sarcosine 2 grams and below, adjust to 1 gram or lower if irritability occur, https://www.mdpi.com/1422-0067/16/10/24475

Side effects from multiple sources

With mild side effects

Ginkgo biloba 240 mg or lower , https://onlinelibrary.wiley.com/doi/10.1155/2013/915691

ashwagandha 500mg or lower, some studies say there are traces of liver damage at low dosage, https://www.psychiatrist.com/jcp/withania-somnifera-extract-for-schizophrenia-symptoms/

Medicine for weight loss from least effective to most

Wegovy/semaglutide: (single glp 1 mechanism) https://www.nejm.org/doi/full/10.1056/NEJMoa2032183

Mounjaro/zepbound/tirzepatide: (duo glp 1+ gip mechanism) https://www.nejm.org/doi/full/10.1056/NEJMoa2206038

Retatrutide:( triple glp 1+gip+ glucagon mechanism, still in phase 2) https://www.nejm.org/doi/full/10.1056/NEJMoa2301972

Side effects comparison tirzepatide vs semaglutide less for tirzepatide:

Side effects comparison tirzepatide vs retatrutide less for tirzepatide: SUN-659 Comparative Efficacy and Safety of Tirzepatide vs Retatrutide in Weight Loss: A Network Meta-Analysis of Clinical Trials - PMC

Side effects comparison oral glp 1 vs injectable less for injectable, more weight loss for injectable but less hba1c reduction: Real-World Comparison of Oral Versus Injectable Semaglutide for the Reduction of Hemoglobin A1C and Weight in Patients with Type 2 Diabetes - PMC

New antipsychotic

Cobenfy(duo mechanism, muscarinic receptor antagonist that cannot cross blood brain barrier, muscarinic receptor agonist that can) slight weight loss in study: Cobenfy (Xanomeline-Trospium Chloride): A New Frontier in Schizophrenia Management - PubMed

Others: feel free to with studies quoted

Again, please consult your doctor before taking any supplements, weight loss medication or new antipsychotic

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Again, please consult your doctor before taking any supplements.

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There was a pinned post on l theanine and sarcosine in the old forum, is it possible for you to create such a pinned post? We can include thing like mounjaro for weight loss or cobenfy for newest antipsychotic to try out…it’s good to give people hope of a life that looks as normal as it can be

No, we have too many pinned topics as it is. We dont want it to become burdensome for new members to navigate the forum. Thank you for the suggestion, though. And thank you for providing the articles for reference as I said.

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