I want to try clozapine

Currently on xeplion and aripiripazole

Still hearing things that aren’t there and paranoid thoughts.

Could clozapine resolve this?

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No,not really .. I’m long time on it,and have voices ..

But it’s best med for me,I can sleep and function ..

I take 300mgs/day

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Clozapine didnt help my voices either still on 150mg a day

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But does it help more then xeplion?

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It’s different,but haven’t tried xeplion,but been on Risperdal Consta for six months ..

I think that are different mechanism meds ..

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I’m on clozapine…350 mg per day. I still have voices but my psychotic symptoms are very mild. It lets me live independently most of the time. I don’t like the increased appetite, and despite using atropine drops I still drool when I sleep.

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Not sure i haven’t tried xeplion

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Xeplion is same as Paliperidone (invega)

It’s European brand.

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I wish I said yes to it a long time ago but I thought I knew better than the doctors

Not that starting it was much of a choice in the end

:person_shrugging:

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I’m not a pdoc, but I think they work better together, I do clozapine and every 3 months I have Paliperidone injections.

My veredict? Clozapine is a must to do drug, and one of the most effective for treating sz, my meds were always clozapine with something, so since I start medication I always used clozapine. Voices didn’t go away, but they got quieter and more manageable.

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Ah gotcha then I have tried it. I had pretty severe akathesia on it and had to take a lot of cogentin that made me super thirsty

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Clozapine does not agree with me. Plus the blood tests. No thank you.

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I’ve been taking clozapine for 7 years.

It’s one of the best meds but doesn’t make me totally sane. I still have symptoms

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Clozapine works well for some people; just a heads up that it might knock you out like an hour or so after you take it.

This is from anecdotal evidence

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I take it at night. It helps me sleep.

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Have you already tried zyprexa? It’s considered by many as the second heaviest drug, only next to clozapine.

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I’m on generic Zyprexa (olanzapine). I take 22.5mg per day every evening. I know this is a little elevated, but I was on 30mg for over two continuous years. It was my Mother’s advice to reduce the dose with a goal target dosage of 20mg per day. I’m just glad to finally be 100% compliant with treatment, as well as having an open mind. I am on the lowest dose of olanzapine I have been on over the past nine consecutive years. And it’s working out so far, which I am proud of. I remember whenever it was my idea to reduce my medication, I always ended up going off the deep end, metaphorically. So I have learned to trust.

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Welcome to the forum @temperature

I guess being compliant is the way to go. Trying to quit meds on my own never went well.

Glad you got to a lower dose, you probably feel better.

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Personally I wouldn’t because when I tried clozapine I passed out every day until I got used to it. Unfortunately I was sedated against my will. I would pass out every night, was very fat and hungry, had breathing troubles and couldn’t communicate. What a nightmare…

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